Article
Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study.
BMC medical genetics - 13 May 2011
Ling Yan, Li Xiaomu, Gu Qian, Chen Hongyan, Lu Daru, Gao Xin
Abstract excerpt
BACKGROUND: Several studies have shown that variants in the glucokinase regulatory protein gene (GCKR) were associated with type 2 diabetes and dyslipidemia. The purpose of this study was to examine whether tag single nucleotide polymorphisms (SNPs) in the GCKR region were associated with type 2 diabetes and related traits in a Han Chinese population and to identify the potential mechanisms underlying these...
Topics
- Adaptor Proteins, Signal Transducing
- Asian People
- Blood Glucose
- Blood Pressure
- Case-Control Studies
- China
- Cholesterol
- Cholesterol, HDL
- Cholesterol, LDL
- Diabetes Mellitus, Type 2
- Female