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Article

Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema.

Allergy - 1 Jul 2010

Jungersted J M, Scheer H, Mempel M, Baurecht H, Cifuentes L, Høgh J K, Hellgren L I, Jemec G B E, Agner T, Weidinger S

Abstract excerpt

BACKGROUND: Prior to the discovery of filaggrin (FLG) mutations, evidence for an impaired skin barrier in atopic dermatitis (AD) has been documented, and changes in ceramide profile, altered skin pH and increased trans-epidermal water loss (TEWL) in patients with AD have been reported. Until now,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20132155
DOI: 10.1111/j.1398-9995.2010.02326.x

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20132155-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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