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Article

Simple association analysis combining data from trios/sibships and unrelated controls.

Genetic epidemiology - 1 Sept 2008

Chen Yi-Hau, Lin Hui-Wen

Abstract excerpt

We consider genetic association analysis that combines data from case-parent trios/sibships and unrelated controls. A general and simple methodology is proposed, using a weighted least-squares approach to combine separate information from the case-parent/case-sibling analysis and the case-unrelated control analysis. The new proposal improves over the existing methods in that it requires no assumptions and...

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PMID: 18348203
DOI: 10.1002/gepi.20325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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