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Article

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.

The EMBO journal - 20 Apr 2011

Freund Adam, Patil Christopher K, Campisi Judith

Abstract excerpt

Cellular senescence suppresses cancer by forcing potentially oncogenic cells into a permanent cell cycle arrest. Senescent cells also secrete growth factors, proteases, and inflammatory cytokines, termed the senescence-associated secretory phenotype (SASP). Much is known about pathways that regulate the senescence growth arrest, but far less is known about pathways that regulate the SASP. We previously showed...

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Identifiers

PMID: 21399611
DOI: 10.1038/emboj.2011.69
PMCID: PMC3102277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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