Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of senescence traits by MAPKs.

GeroScience - 1 Apr 2020

Anerillas Carlos, Abdelmohsen Kotb, Gorospe Myriam

Abstract excerpt

A phenotype of indefinite growth arrest acquired in response to sublethal damage, cellular senescence affects normal aging and age-related disease. Mitogen-activated protein kinases (MAPKs) are capable of sensing changes in cellular conditions, and in turn elicit adaptive responses including cell senescence. MAPKs modulate the levels and function of many proteins, including proinflammatory factors and factors in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to Mitogen-Activated Protein Kinases
Share to p38 Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 32300964
DOI: 10.1007/s11357-020-00183-3
PMCID: PMC7205942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of senescence traits by MAPKs.PMID 32300964Read ↗

Stress-Activated MAP Kinase Cascades in Cellular SenescenceSemantic proximity Read ↗

Cellular senescence: Molecular mechanisms and pathogenicitySemantic proximity Read ↗

From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes.Semantic proximity Read ↗

Hallmarks and mechanisms of cellular senescence in aging and diseaseSemantic proximity Read ↗

Hallmarks of cellular senescence: biology, mechanisms, regulationsSemantic proximity Read ↗

Hallmarks of Cellular Senescence.Semantic proximity Read ↗

Targeting cellular senescence to combat cancer and ageingSemantic proximity Read ↗

Molecular signaling and genetic pathways of senescence: Its role in tumorigenesis and agingSemantic proximity Read ↗

Cellular Senescence: Aging, Cancer, and InjurySemantic proximity Read ↗

Understanding cellular senescence: pathways involved, therapeutics and longevity aidingSemantic proximity Read ↗

Senescence and senolysis in cancer: The latest findingsSemantic proximity Read ↗

The role of p21 in cellular senescence and aging-related diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.