Article
HIV-1 adaptation to NK-cell-mediated immune pressure.
Nature - 3 Aug 2011
Alter Galit, Heckerman David, Schneidewind Arne, Fadda Lena, Kadie Carl M, Carlson Jonathan M, Oniangue-Ndza Cesar, Martin Maureen, Li Bin, Khakoo Salim I, Carrington Mary, Allen Todd M, Altfeld Marcus
Abstract excerpt
Natural killer (NK) cells have an important role in the control of viral infections, recognizing virally infected cells through a variety of activating and inhibitory receptors. Epidemiological and functional studies have recently suggested that NK cells can also contribute to the control of HIV-1 infection through recognition of virally infected cells by both activating and inhibitory killer immunoglobulin-like...
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