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Article

Efficient electrophoretic method to remove neutral additives from protein solutions followed by mass spectrometry analysis.

Analytical chemistry - 1 Apr 2011

Pai Pei-Jing, Cologna Stephanie M, Russell William K, Vigh Gyula, Russell David H

Abstract excerpt

A mass spectrometry (MS)-compatible, isoelectric point-based separation method for removal of neutral additives from protein solutions is described. The separation is performed by electrophoretic migration and trapping using a device referred to as membrane separated wells for isoelectric focusing and trapping (MSWIFT). Electrophoretic separation in the MSWIFT device is fast; the entire process can be carried out...

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PMID: 21395231
DOI: 10.1021/ac1029743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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