Hydrophobic interaction capillary electrochromatography of protein mutants. Use of lipid-based liquid crystalline nanoparticles as pseudostationary phase.

Abstract excerpt

Nanoparticle-based hydrophobic interaction-capillary electrochromatography was utilized for separation of proteins with similar mass-to-charge ratio at neutral pH without organic modifier. Lipid-based liquid crystalline nanoparticles were prepared and used as pseudostationary phase,benefiting from their high biocompatibility, ease of preparation,and suspension stability at high concentrations.Use of laser-induced...

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