Article

Native Ion Mobility Mass Spectrometry: when Gas Phase Ion Structures Depend on the Electrospray Charging Process

2019-02-08

Abstract excerpt

Ion mobility spectrometry (IMS) has become popular to characterize biomolecule folding. Numerous studies have shown that proteins that are folded in solution remain folded in the gas phase, whereas proteins that are unfolded in solution adopt more extended conformations in the gas phase. Here, we discuss how general this tenet is. We studied single-stranded DNAs (human telomeric cytosine-rich sequences with CCCTAA...

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Literature Corpus work: 17ee9d45-4ea7-58ef-b483-2b1b64c129bb
DOI: 10.26434/chemrxiv.7500617.v2

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