Article

Preanalytical Strategies for Native Mass Spectrometry Analysis of Protein Modifications, Complexes, and Higher-Order Structures<b></b>

2025-10-21

Abstract excerpt

Proteins are essential biological macromolecules that play key regulatory roles in all biological processes. Abnormalities in these processes are often reflected in proteins, manifesting as changes in their structure, sequence, folding state, stoichiometry, or spatial and temporal distribution. Proteins serve as biological targets for drugs and other therapeutics and can also function as therapeutic agents to rest...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 69d2da04-591c-507c-a6dc-9ab3ce7f5110
DOI: 10.20944/preprints202510.1566.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Preanalytical Strategies for Native Mass Spectrometry Analysis of Protein Modifications, Complexes, and Higher-Order Structures<b></b>DOI 10.20944/preprints202510.1566.v1Read

Mass-spectrometric exploration of proteome structure and function.Semantic proximity Read

Proteomics Techniques in Focus: From Basics to Advanced ApplicationsSemantic proximity Read

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark MatterSemantic proximity Read

Mass Spectrometry-Based Techniques Towards OMICS 2.0Semantic proximity Read

Characterization of protein variants and post-translational modifications: ESI-MSn analyses of intact proteins eluted from polyacrylamide gels.Semantic proximity Read

Proteomics in the COVID‐19 Battlefield: First Semester Check‐UpSemantic proximity Read

Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism.Semantic proximity Read

Protein Termini and Their Modifications Revealed by Positional ProteomicsSemantic proximity Read

Structural and Functional Consequences of Age-Related Isomerization in α-CrystallinsSemantic proximity Read

HXMS: a standardized file format for HX-MS dataSemantic proximity Read

Mass spectrometry in protein structural analysis.Semantic proximity Read

A peptide-centric local stability assay to unveil protein targets of diverse ligandsSemantic proximity Read