Definition of adenovirus type 5 functions involved in the induction of chromosomal aberrations in human cells.

doi:10.1099/0022-1317-71-4-801

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Article

Definition of adenovirus type 5 functions involved in the induction of chromosomal aberrations in human cells.

The Journal of general virology - 1 Apr 1990

Caporossi D, Bacchetti S

Abstract excerpt

Infection of human embryonic kidney cells with adenovirus type 5 (Ad5) induces aberrations (gaps and breaks) in the cell chromosomes. We have conducted a study utilizing a large number of Ad5 mutants to identify the viral functions that are responsible for the occurrence of cytogenetic damage. Th...

Topics

Adenovirus Early Proteins
Adenoviruses, Human
Chromosome Aberrations
DNA Replication
Gene Expression Regulation, Viral
Humans
Mutation
Oncogene Proteins, Viral
Virus Replication

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