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Article

Definition of adenovirus type 5 functions involved in the induction of chromosomal aberrations in human cells.

The Journal of general virology - 1 Apr 1990

Caporossi D, Bacchetti S

Abstract excerpt

Infection of human embryonic kidney cells with adenovirus type 5 (Ad5) induces aberrations (gaps and breaks) in the cell chromosomes. We have conducted a study utilizing a large number of Ad5 mutants to identify the viral functions that are responsible for the occurrence of cytogenetic damage. The results of our investigation have indicated that expression of the gene products of the Ad5 early region 1A (E1A) is...

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Identifiers

PMID: 2139107
DOI: 10.1099/0022-1317-71-4-801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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