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Article

Multiple functions of the adenovirus DNA-binding protein are required for efficient viral DNA synthesis.

Virology - 1 Sept 1993

Brough D E, Droguett G, Horwitz M S, Klessig D F

Abstract excerpt

Mutational analysis within the amino-terminal (N-t) domain of the adenovirus DNA-binding protein (DBP) defined a region (aa 2-38) important for DBP function. Several viruses carrying lesions in this region of DBP showed reduced accumulation of viral DNA and infectious virions. Characterization of one of these mutants, H5in800, indicated that the N-t domain affects viral DNA synthesis in vivo. The reduction in DNA...

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Source

Identifiers

PMID: 8356799
DOI: 10.1006/viro.1993.1475

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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