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Article

Multiple functions of the adenovirus DNA-binding protein are required for efficient viral DNA synthesis.

Virology - 1 Sept 1993

Brough D E, Droguett G, Horwitz M S, Klessig D F

Abstract excerpt

Mutational analysis within the amino-terminal (N-t) domain of the adenovirus DNA-binding protein (DBP) defined a region (aa 2-38) important for DBP function. Several viruses carrying lesions in this region of DBP showed reduced accumulation of viral DNA and infectious virions. Characterization of...

Topics

Adenoviruses, Human
Cell Line
DNA Replication
DNA, Single-Stranded
DNA, Viral
DNA-Binding Proteins
Gene Expression Regulation, Viral
Genetic Complementation Test
HeLa Cells
Humans
Kinetics
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Proteins

Source

Identifiers

PMID: 8356799
DOI: 10.1006/viro.1993.1475

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8356799-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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