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Article

BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells

2 Mar 2011

Abstract excerpt

Cancer stem cells (CSCs) are initiating cells in colorectal cancer (CRC). Colorectal tumours undergo epithelial to mesenchymal transition (EMT)-like processes at the invasive front, enabling invasion and metastasis, and recent studies have linked this process to the acquisition of stem cell-like properties. It is of fundamental importance to understand the molecular events leading to the establishment of cancer...

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PMID: 21365650
DOI: 10.1002/ijc.26029

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