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Article

Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells.

Experimental biology and medicine (Maywood, N.J.) - 1 May 2011

Palena Claudia, Fernando Romaine I, Litzinger Mary T, Hamilton Duane H, Huang Bruce, Schlom Jeffrey

Abstract excerpt

The switch of carcinoma cells from an epithelial to a mesenchymal-like phenotype, via a process designated 'epithelial-to-mesenchymal transition (EMT),' has been recognized as a relevant step in the metastasis of solid tumors. Additionally, this phenotypic switch of carcinoma cells has been associated with the acquisition of tumor resistance mechanisms that reduce the antitumor effects of radiation, chemotherapy...

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Identifiers

PMID: 21427233
DOI: 10.1258/ebm.2011.010367
PMCID: PMC3508693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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