Article
Impact of WWOX alterations on p73, ΔNp73, p53, cell proliferation and DNA ploidy in salivary gland neoplasms.
Oral diseases - 1 Sept 2011
Gomes C C, Diniz M G, Oliveira C S, Tavassoli M, Odell E W, Gomez R S, De Marco L
Abstract excerpt
OBJECTIVE: WWOX gene is altered in a variety of neoplasms. Wwox is pro-apoptotic through interaction with p73 and may be involved in chromosomal stability by interaction with p73 and p53. The aims of this study were to characterize WWOX transcription, methylation status and immunoexpression in salivary neoplasms and to determine whether these were associated with p73, p53, cell proliferation and DNA ploidy....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
