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Article

Epigenetic and genetic alterations affect the WWOX gene in head and neck squamous cell carcinoma.

PloS one - 1 Jan 2015

Ekizoglu Seda, Bulut Pelin, Karaman Emin, Kilic Erkan, Buyru Nur

Abstract excerpt

Different types of genetic and epigenetic changes are associated with HNSCC. The molecular mechanisms of HNSCC carcinogenesis are still undergoing intensive investigation. WWOX gene expression is altered in many cancers and in a recent work reduced WWOX expression has been associated with miR-134 expression in HNSCC. In this study we investigated the WWOX messenger RNA expression levels in association with the...

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Share to Carcinoma, Squamous Cell
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Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 25612104
DOI: 10.1371/journal.pone.0115353
PMCID: PMC4303423

Genes

WWOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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