Article
Assessment of TP53 mutations in benign and malignant salivary gland neoplasms.
PloS one - 1 Jan 2012
Gomes Carolina Cavaliéri, Diniz Marina Gonçalves, Orsine Lissur Azevedo, Duarte Alessandra Pires, Fonseca-Silva Thiago, Conn Brendan I, De Marco Luiz, Pereira Cláudia Maria, Gomez Ricardo Santiago
Abstract excerpt
Despite advances in the understanding of the pathogenesis of salivary gland neoplasms (SGN), the molecular pathways associated with enhanced tumor growth and cell survival remain to be established. The aim of the present study was to investigate whether TP53 mutations are relevant to SGN pathogenesis and if they impact on p53 protein expression. The study included 18 benign and 18 malignant SGN samples. Two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.