Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WWP1 gene is a potential molecular target of human oral cancer.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Aug 2013

Lin Ju-Hwa, Hsieh Shu-Chen, Chen Jia-Ni, Tsai Ming-Hsui, Chang Chia-Che

Abstract excerpt

OBJECTIVE: This study investigates the oncogenic role of WWP1, an ubiquitin ligase linked to tumor promotion, in oral cancer. STUDY DESIGN: An array-based comparative genomic hybridization was used to detect chromosomal changes in 10 oral cancer specimens. An additional 59 specimens and 6 cultured oral cancer cells were further examined to evaluate changes in the DNA copy number and messenger RNA (mRNA) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Gene Knockdown Techniques

Share to Gene Targeting

Share to Mouth Neoplasms

Share to Oncogenes

Share to RNA, Small Interfering

Source

Identifiers

PMID: 23849376
DOI: 10.1016/j.oooo.2013.05.006

Genes

WWP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WWP1 gene is a potential molecular target of human oral cancer.PMID 23849376Read ↗

WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in miceSemantic proximity Read ↗

WWP1 E3 ligase at the crossroads of health and diseaseSemantic proximity Read ↗

Functional genetic variant in the Kozak sequence of WW domain-containing oxidoreductase (WWOX) gene is associated with oral cancer risk.Semantic proximity Read ↗

[Abnormal expression of WWP1 in chronic lymphocytic leukemia and its clinical significance].Semantic proximity Read ↗

Tumour‐promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicatorSemantic proximity Read ↗

Overexpression of small ubiquitin-related modifier-1 and sumoylated Mdm2 in oral squamous cell carcinoma: Possible involvement in tumor proliferation and prognosisSemantic proximity Read ↗

WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinomaSemantic proximity Read ↗

Characterization of the tumor suppressor gene <i>WWOX</i> in primary human oral squamous cell carcinomasSemantic proximity Read ↗

Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.Semantic proximity Read ↗

E3 ubiquitin ligase WWP2 as a promising therapeutic target for diverse human diseasesSemantic proximity Read ↗

Molecular Biology of Human Oral CancerSemantic proximity Read ↗

Molecular Functions of WWOX Potentially Involved in Cancer DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.