Article
Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jan 2006
Ebrahimi Majid, Wahlin Ylva-Britt, Coates Philip J, Sjöström Björn, Nylander Karin
Abstract excerpt
BACKGROUND: Oral lichen planus (OLP) and graft-vs.-host disease (GVHD) are conditions with increased risk of malignant transformation to squamous cell carcinoma of the head and neck (SCCHN). The p63 gene encodes six different proteins and is expressed at high levels in SCCHN. METHODS: Biopsies from patients diagnosed with OLP and GVHD were analysed for p63 protein expression using antibodies distinguishing...
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