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Article

Aneuploidy and loss of heterozygosity as risk markers for malignant transformation in oral mucosa

12 Feb 2021

Abstract excerpt

The ability to predict malignant transformation in oral potentially malignant disorders would inform targeted treatment, provide prognostic information and allow secondary prevention. DNA ploidy and loss of heterozygosity assays are already in clinical use, and loss of heterozygosity has been used in prospective clinical trials. This review appraises published evidence of predictive ability and explores...

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PMID: 33577101
DOI: 10.1111/odi.13797

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