Article
The salivary tip of the p53 mutagenesis iceberg: novel insights.
Cancer biomarkers : section A of Disease markers - 1 Jan 2009
Ben-Izhak Ofer, Laster Zvi, Akrish Sharon, Muska Egon, Gan Shlomit, Nagler Rafael M
Abstract excerpt
Salivary malignancies are rare, heterogeneous, unpredictable in their clinical behavior and seldom studied. This study focused on examining the expression of mutated p53, the most prevalent mutated gene related to human cancer, in a rather large cohort of salivary malignancies (n = 70) and for a prolonged period (20 years). P53 was found to be a most powerful predictor for poor survival and more so when the tumor...
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