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Article

Kalrn promoter usage and isoform expression respond to chronic cocaine exposure.

BMC neuroscience - 17 Feb 2011

Mains Richard E, Kiraly Drew D, Eipper-Mains Jodi E, Ma Xin-Ming, Eipper Betty A

Abstract excerpt

BACKGROUND: The long-term effects of cocaine on behavior are accompanied by structural changes in excitatory glutamatergic synapses onto the medium spiny neurons of the striatum. The Kalrn gene encodes several functionally distinct isoforms; these multidomain guanine nucleotide exchange factors (GEFs) contain additional domains known to interact with phosphatidylinositides as well as with a number of different...

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Identifiers

PMID: 21329509
DOI: 10.1186/1471-2202-12-20
PMCID: PMC3048553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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