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Article

Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo.

European journal of endocrinology - 1 May 2011

Olsson Anders H, Rönn Tina, Ladenvall Claes, Parikh Hemang, Isomaa Bo, Groop Leif, Ling Charlotte

Abstract excerpt

CONTEXT: Mitochondrial ATP production is important in the regulation of glucose-stimulated insulin secretion. Genetic factors may modulate the capacity of the β-cells to secrete insulin and thereby contribute to the risk of type 2 diabetes. OBJECTIVE: The aim of this study was to identify genetic loci in or adjacent to nuclear-encoded genes of the oxidative phosphorylation (OXPHOS) pathway that are associated...

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Source

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Identifiers

PMID: 21325017
DOI: 10.1530/EJE-10-0995
PMCID: PMC3080761

Genes

NDUFC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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