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Article

Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.

Diabetes - 1 Nov 2008

Gaulton Kyle J, Willer Cristen J, Li Yun, Scott Laura J, Conneely Karen N, Jackson Anne U, Duren William L, Chines Peter S, Narisu Narisu, Bonnycastle Lori L, Luo Jingchun, Tong Maurine, Sprau Andrew G, Pugh Elizabeth W, Doheny Kimberly F, Valle Timo T, Abecasis Gonçalo R, Tuomilehto Jaakko, Bergman Richard N, Collins Francis S, Boehnke Michael, Mohlke Karen L

Abstract excerpt

OBJECTIVE: Type 2 diabetes is a common complex disorder with environmental and genetic components. We used a candidate gene-based approach to identify single nucleotide polymorphism (SNP) variants in 222 candidate genes that influence susceptibility to type 2 diabetes. RESEARCH DESIGN AND METHODS: In a case-control study of 1,161 type 2 diabetic subjects and 1,174 control Finns who are normal glucose tolerant, we...

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Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

Share to Glucose Transporter Type 2

Share to Phosphoric Diester Hydrolases

Share to Potassium Channels, Inwardly Rectifying

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Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 18678618
DOI: 10.2337/db07-1731
PMCID: PMC2570412

Genes

ENPP1
KCNJ11
NRF1
PPARG
RAPGEF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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