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Article

Understanding Genetic Heterogeneity in Type 2 Diabetes by Delineating Physiological Phenotypes: SIRT1 and its Gene Network in Impaired Insulin Secretion.

The review of diabetic studies : RDS - 1 Jan 2016

Ali Shafat, Nafis Shazia, Kalaiarasan Ponnusamy, Rai Ekta, Sharma Swarkar, Bamezai Rameshwar N

Abstract excerpt

Type 2 diabetes (T2D) is a chronic metabolic disease which shows an exponential increase in all parts of the world. However, the disease is controllable by early detection and modified lifestyle. A series of factors have been associated with the pathogenesis of diabetes, and genes are considered to play a critical role. The individual risk of developing T2D is determined by an altered genetic background of the...

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Share to Diabetes Mellitus, Type 2
Share to Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Insulin

Share to Insulin Resistance

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 27563694
DOI: 10.1900/RDS.2016.13.17
PMCID: PMC5291180

Genes

SIRT1
HHEX
PGC
UCP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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