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Article

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.

Retrovirology - 16 Feb 2011

Votteler Jörg, Neumann Liane, Hahn Sabine, Hahn Friedrich, Rauch Pia, Schmidt Kerstin, Studtrucker Nicole, Solbak Sara M Ø, Fossen Torgils, Henklein Peter, Ott David E, Holland Gudrun, Bannert Norbert, Schubert Ulrich

Abstract excerpt

BACKGROUND: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic regions of the HIV-1 gag gene, the 52 amino acid peptide binds at least to two cellular budding factors (Tsg101 and ALIX), is a substrate for phosphorylation, ubiquitination, and sumoylation,...

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Share to Capsid
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to Magnetic Resonance Spectroscopy

Share to Microscopy, Electron, Transmission

Share to Virion

Share to Virus Assembly

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Source

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Identifiers

PMID: 21324168
DOI: 10.1186/1742-4690-8-11
PMCID: PMC3049138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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