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Article

The PTAP sequence within the p6 domain of human immunodeficiency virus type 1 Gag regulates its ubiquitination and MHC class I antigen presentation.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2011

Hahn Sabine, Setz Christian, Wild Julia, Schubert Ulrich

Abstract excerpt

Endogenous peptides presented by MHC class I (MHC-I) molecules are mostly derived from de novo synthesized, erroneous proteins, so-called defective ribosomal products (DRiPs), which are rapidly degraded via the ubiquitin-proteasome pathway. We have previously shown that the HIV-1 Gag protein repr...

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Share to Amino Acid Motifs
Share to Antigen Presentation
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Proteasome Endopeptidase Complex

Share to Ribosomes

Share to RNA, Small Interfering

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Source

Identifiers

PMID: 21482733
DOI: 10.4049/jimmunol.1003764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21482733-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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