Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Late Domain of Human Immunodeficiency Virus Type 1 p6 Promotes Virus Release in a Cell Type-Dependent Manner

1 Jan 2002

Abstract excerpt

The p6 domain of human immunodeficiency virus type 1 (HIV-1) is located at the C terminus of the Gag precursor protein Pr55(Gag). Previous studies indicated that p6 plays a critical role in HIV-1 particle budding from virus-expressing HeLa cells. In this study, we performed a detailed mutational analysis of the N terminus of p6 to map the sequences required for efficient virus release. We observed that the highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11739676
DOI: 10.1128/jvi.76.1.105-117.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Late Domain of Human Immunodeficiency Virus Type 1 p6 Promotes Virus Release in a Cell Type-Dependent MannerPMID 11739676Read ↗

p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing proteaseSemantic proximity Read ↗

Role of the C terminus Gag protein in human immunodeficiency virus type 1 virion assembly and maturation.Semantic proximity Read ↗

Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.Semantic proximity Read ↗

Mutations of the human immunodeficiency virus type 1 p6Gag domain result in reduced retention of Pol proteins during virus assembly.Semantic proximity Read ↗

The central region of human immunodeficiency virus type 1 p6 protein (Gag residues S14-I31) is dispensable for the virus in vitro.Semantic proximity Read ↗

The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPXnL Late Domains to Recruit the Cellular Machinery Necessary for Viral BuddingSemantic proximity Read ↗

trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1.Semantic proximity Read ↗

Cell-type-dependent targeting of human immunodeficiency virus type 1 assembly to the plasma membrane and the multivesicular body.Semantic proximity Read ↗

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function.Semantic proximity Read ↗

Uncoupling Human Immunodeficiency Virus Type 1 gag and pol Reading Frames: Role of the Transframe Protein p6* in Viral ReplicationSemantic proximity Read ↗

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.Semantic proximity Read ↗

Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.