Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.

Journal of virology - 1 Mar 2011

Dussupt Vincent, Sette Paola, Bello Nana F, Javid Melodi P, Nagashima Kunio, Bouamr Fadila

Abstract excerpt

The p6 region of HIV-1 Gag contains two late (L) domains, PTAP and LYPXnL, that bind the cellular proteins Tsg101 and Alix, respectively. These interactions are thought to recruit members of the host fission machinery (ESCRT) to facilitate HIV-1 release. Here we report a new role for the p6-adjac...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to DNA-Binding Proteins
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

Share to HIV Infections

Share to Protein Structure, Tertiary

Share to Virus Release

Source

Open in PubMed Open full text

Identifiers

PMID: 21159863
DOI: 10.1128/JVI.01562-10
PMCID: PMC3067763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21159863-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.PMID 21159863Read ↗

The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPXnL Late Domains to Recruit the Cellular Machinery Necessary for Viral BuddingSemantic proximity Read ↗

Budding of retroviruses utilizing divergent L domains requires nucleocapsid.Semantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Nucleocapsid p1 Confers ESCRT Pathway DependenceSemantic proximity Read ↗

PYRE insertion within HIV-1 subtype C p6-Gag functions as an ALIX-dependent late domain.Semantic proximity Read ↗

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.Semantic proximity Read ↗

Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site.Semantic proximity Read ↗

The Late Domain of Human Immunodeficiency Virus Type 1 p6 Promotes Virus Release in a Cell Type-Dependent MannerSemantic proximity Read ↗

Efficient and Specific Rescue of Human Immunodeficiency Virus Type 1 Budding Defects by a Nedd4-Like Ubiquitin LigaseSemantic proximity Read ↗

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function.Semantic proximity Read ↗

Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression.Semantic proximity Read ↗

Role of the C terminus Gag protein in human immunodeficiency virus type 1 virion assembly and maturation.Semantic proximity Read ↗

Cumulative mutations of ubiquitin acceptor sites in human immunodeficiency virus type 1 gag cause a late budding defect.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.