Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The HIV-TSG101 interface: recent advances in a budding field.

Trends in microbiology - 1 Feb 2003

Freed Eric O

Abstract excerpt

Efficient budding of HIV from the plasma membrane requires a small peptide motif, Pro-Thr/Ser-Ala-Pro (PTAP), located near the amino terminus of the p6 Gag protein. Studies from several laboratories have demonstrated that the ability of p6 to stimulate HIV budding requires a direct interaction between the PTAP motif and the host endosomal sorting protein TSG101. The structure of the PTAP-TSG101 binding site has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to DNA-Binding Proteins
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, gag

Share to HeLa Cells

Share to Ubiquitins

Share to Virus Replication

Source

Identifiers

PMID: 12598123
DOI: 10.1016/s0966-842x(02)00013-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The HIV-TSG101 interface: recent advances in a budding field.PMID 12598123Read ↗

Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 proteinSemantic proximity Read ↗

Defects in human immunodeficiency virus budding and endosomal sorting induced by TSG101 overexpression.Semantic proximity Read ↗

Tsg101 UEV Interaction with Nedd4 HECT Relieves E3 Ligase Auto-Inhibition, Promoting HIV-1 Assembly and CA-SP1 Maturation Cleavage.Semantic proximity Read ↗

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly.Semantic proximity Read ↗

Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag.Semantic proximity Read ↗

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function.Semantic proximity Read ↗

Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.Semantic proximity Read ↗

The protein network of HIV budding.Semantic proximity Read ↗

Refined study of the interaction between HIV-1 p6 late domain and ALIX.Semantic proximity Read ↗

Essential and supporting host cell factors for HIV-1 buddingSemantic proximity Read ↗

Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4Semantic proximity Read ↗

Variability in the P6gag domains of HIV-1 involved in viral budding.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.