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Article

Role of the C terminus Gag protein in human immunodeficiency virus type 1 virion assembly and maturation.

The Journal of general virology - 1 Dec 1995

Yu X F, Matsuda Z, Yu Q C, Lee T H, Essex M

Abstract excerpt

Lentiviral Gag polyproteins have a proline-rich protein, p6, at their C terminus. There are conflicting reports about the function of p6 in virus release. In the present work, mutants that affect p6 of human immunodeficiency virus type 1 (HIV-1) Gag polyprotein were constructed and analysed. None of the mutants prevented virus release completely; however, detachment of budding particles was less efficient as...

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Identifiers

PMID: 8847526
DOI: 10.1099/0022-1317-76-12-3171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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