Article

Embryoid bodies facilitate comparative analysis of gene expression in humans and chimpanzees across dozens of cell types

2022-07-21

Abstract excerpt

Comparative gene expression studies in apes are fundamentally limited by the challenges associated with sampling across different tissues. Here, we used single-cell RNA-sequencing of embryoid bodies ( EBs ) to collect transcriptomic data from over 70 cell types in three humans and three chimpanzees. We found hundreds of genes whose regulation is conserved across cell types, as well as genes whose regulation likel...

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Literature Corpus work: 7e7824a0-417a-537d-a085-3b161f4b39dd
DOI: 10.1101/2022.07.20.500831

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