Article

DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts

2022-07-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> DNA methylation is an important epigenetic modification which has numerous roles in modulating genome function. Its levels are spatially correlated across the genome, typically high in repressed regions but low in transcription factor (TF) binding sites and active regulatory regions. However, the mechanisms establishing genome-wide and TF binding site methylation patterns ar...

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Literature Corpus work: 808cfab4-74bc-5a57-9e15-2a0a3ed32fbe
DOI: 10.1101/2022.07.21.500978

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