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Article

Some novel features of IDH1-mutated acute myeloid leukemia revealed in Chinese patients.

Leukemia research - 1 Oct 2011

Zhang Yiqun, Wei Hui, Wang Min, Huai Lei, Mi Yingchang, Zhang Yizhi, Lin Dong, Liu Bingcheng, Li Wei, Zhou Chunlin, Rao Qing, Wang Jianxiang

Abstract excerpt

Mutations of isocitrate dehydrogenase 1 (IDH1) have recently been reported in acute myeloid leukemia (AML). However, the characteristics of IDH1-mutated AML are still not known clearly. We analyzed 416 Chinese AML patients and found 28 patients (6.7%) carried this mutation. One homozygous IDH1 mutant in AML was found. The IDH1 mutations were associated with NPM1 mutations (P=0.043) and could coexist with...

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Source

Identifiers

PMID: 21316759
DOI: 10.1016/j.leukres.2011.01.019

Genes

IDH1
MYH11
NPM1
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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