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[Detection of isocitrate dehydrogenase 1 gene mutation in 205 AML patients and its clinical significance].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2012

Shang Zhen, Wang Di, Xiao Ming, Geng Zhe, Wang Hai-Xia, Wang Jue, Xu Yan-Ling, Li Tong-Juan, Zhou Jian-Feng, Li Chun-Rui

Abstract excerpt

This study was purposed to detect the mutation of isocitrate dehydrogenase 1 (IDH-1) gene in patients with acute myeloid leukemia (AML) and to explore its clinical significance. The genomic DNA was extracted from mononuclear cells (MNC) of bone marrow or peripheral blood in 205 adult AML patients, the exon 4 of IDH1 gene was amplified by PCR, then the sequencing and comparison were performed. The results showed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23257422

Genes

IDH1
FLT3
NPM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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