Article
[Research advances of IDH gene mutation and AML].
Zhongguo shi yan xue ye xue za zhi - 1 Oct 2014
Sun Ming-Dong, Zheng Yong-Qin
Abstract excerpt
The isocitrate dehydrogenase (IDH) gene mutation has been recently found, which may be involved in the occurrence of leukemia. The incidence of IDH gene mutation in the patients with adult acute myeloid leukemia (AML) is high, especially in the AML patients with normal karyotype. Different subtype and molecular biology of IDH display a different effect on the AML prognosis. This gene mutation is related with...
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