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[IDH1 Gene Mutation and Its Clinical Significance in patients with Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2015

Wei Ji-Feng, Qiu Hui-Ying, Chen Guang-Hua, Wang Ying, Chen Zhe, Liu Hui-Jie, Mao Jian-Ping, Jia Tao, Xue Lian-Guo, Cai Zhi-Mei, Zhu Yuan-Xin, Zhao Li-Dong

Abstract excerpt

OBJECTIVE: To evaluate the incidence rate of IDH1 in acute myeloid leukemia and analyze its effect on clinical characteristics and prognosis. METHODS: Mononuclear cells in bone marrow samples were collected from 192 adult patients with newly diagnosed AML. Polymerase chain reaction (PCR) and direct sequencing were used to amplify exon 4 of IDH1 gene, the gene sequencing was used to analyze the gene mutations, at...

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Share to Abnormal Karyotype
Share to Isocitrate Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 26524018
DOI: 10.7534/j.issn.1009-2137.2015.05.006

Genes

IDH1
FLT3
KIT
NPM1
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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