Article
Mutation profile and associated clinical features in Chinese patients with cytogenetically normal acute myeloid leukemia.
International journal of laboratory hematology - 1 Aug 2018
Wang S, Zhang Y-X, Huang T, Sui J-N, Lu J, Chen X-J, Wang K-K, Xi X-D, Li J-M, Huang J-Y, Chen B
Abstract excerpt
INTRODUCTION: Cytogenetically normal acute myeloid leukemia (CN-AML), which accounted for nearly half of total AML patients, is a highly heterogeneous subset of AML. The specific genetic profile and the ethnic features of CN-AML are worth to be studied. METHODS: Using deep sequencing technology, we detected the mutation pattern of 39 genes in 152 Chinese CN-AML patients and analyzed their clinical features....
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