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Article

Prevalence and Clinical Effect of IDH1 and IDH2 Mutations Among Cytogenetically Normal Acute Myeloid Leukemia Patients.

Clinical lymphoma, myeloma & leukemia - 1 Sept 2015

Aref Salah, Kamel Areida El Sayed, Abdel Aaal Mohamed Fathy, Adam Ola Mohamed, El-Ghonemy Mohamed Sabry, El-Baiomy Mohamed Ali, Zeid Tarek Abou

Abstract excerpt

BACKGROUND: The frequencies of isocitrate dehydrogenase (IDH) 1 and IDH2 mutations among patients with de novo acute myeloid leukemia (AML) are different among different ethnic groups. The aim of this study was to determine the frequencies of IDH1 and IDH2 mutations among Egyptian AML patients and its effect on patient outcomes. PATIENTS AND METHODS: This study was conducted in 211 adult patients (104 men; 107...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26189213
DOI: 10.1016/j.clml.2015.05.009

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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