Article
[Research Advances of IDH2 Gene Mutation in Acute Myeloid Leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2016
Zhao Yan-Xia, Shen Xu-Liang
Abstract excerpt
Acute myeloid leukemia (AML) is a malignant clonal hematologic disease from hematopoietic stem and progenitor cells. The isocitrate dehychogenase 2 (IDH2) gene mutation has been recently found, which may be associated with the course of AML. The incidence of IDH2 gene mutation in the patients with acute myeloid leukemia is high, especially in the AML patients with normal karyotype. Different subtypes of IDH2...
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