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Article

IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders.

Biochemical and biophysical research communications - 12 Nov 2010

Zou Yang, Zeng Yun, Zhang Deng-Feng, Zou Shan-Hua, Cheng Yun-Feng, Yao Yong-Gang

Abstract excerpt

Frequent mutations in the isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) have been identified in gliomas and acute myeloid leukemia (AML). Our aim is to assess whether IDH mutations were presented in Chinese patients with various hematological disorders. In this study, we screened the IDH1 and IDH2 mutations in a cohort of 456 Chinese patients with various hematological malignancies and disorders. We...

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Source

Identifiers

PMID: 20946881
DOI: 10.1016/j.bbrc.2010.10.038

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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