Article
HBV core region variability: effect of antiviral treatments on main epitopic regions.
Antiviral therapy - 1 Jan 2011
Homs Maria, Jardi Rosendo, Buti Maria, Schaper Melanie, Tabernero David, Fernandez-Fernandez Pilar, Quer Josep, Esteban Rafael, Rodriguez-Frias Francisco
Abstract excerpt
BACKGROUND: Amino acid (AA) changes in specific hepatitis B core antigen (HBcAg) regions were assessed in patients infected with chronic hepatitis B (CHB) after a 12-month untreated period and after receiving antiviral therapy (interferon, lamivudine or adefovir dipivoxil), and in inactive hepatitis B surface antigen-positive carriers. METHODS: Samples corresponding to different time points in 76 CHB cases (64...
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