Hepatitis B virus precore/core variation and interferon therapy.

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Article

Hepatitis B virus precore/core variation and interferon therapy.

Hepatology (Baltimore, Md.) - 1 Nov 1995

Fattovich G, McIntyre G, Thursz M, Colman K, Giuliano G, Alberti A, Thomas H C, Carman W F

Abstract excerpt

Precore/core genes from hepatitis B e antigen (HBeAg)-positive and antibody to HBeAg (anti-HBe) positive individuals with active hepatitis have been analyzed to search for correlations with response to interferon before and after treatment. Pretreatment, no precore stop codon mutants were detected, even at the 3% level, in HBeAg-positive responders or nonresponders. In anti-HBe-positive patients, precore mutants...

Topics

Adolescent
Adult
Amino Acid Sequence
Antiviral Agents
Base Sequence
Drug Resistance
Female
Hepatitis B
Hepatitis B e Antigens
Hepatitis B virus
Humans
Interferons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Mutation

Sequence Analysis

Viral Core Proteins

Source

Open in PubMed

Identifiers

PMID: 7590647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7590647-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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