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Article

Selection of hepatitis B virus variants with aminoacid substitutions inside the core antigen during interferon-alpha therapy.

Journal of medical virology - 1 Dec 2000

Radecke K, Protzer U, Trippler M, Meyer Zum Büschenfelde K H, Gerken G

Abstract excerpt

The hepatitis B virus (HBV) core antigen carries many epitopes relevant for B and T cell response that show aminoacid variation during viral infection. In a longitudinal analysis, sequential serum samples of 15 patients that suffered from chronic HBV infection were collected before, during, and after high-dose IFN-alpha treatment. The HBV preCore/Core (preC/C) sequence of the selected samples in each patient was...

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Source

Identifiers

PMID: 11074477
DOI: 10.1002/1096-9071(200012)62:4<479::aid-jmv13>3.0.co;2-m

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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