Core variability does not affect response to interferon alpha in HBeAg negative chronic hepatitis B.

doi:10.1016/s0168-8278(98)80050-0

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Core variability does not affect response to interferon alpha in HBeAg negative chronic hepatitis B.

Journal of hepatology - 1 Sept 1998

Alexopoulou A, Owsianka A M, Kafiri G, Dourakis S P, Carman W F, Hadziyannis S J

Abstract excerpt

BACKGROUND/AIMS: The pre-core stop codon variant (A 1896) of hepatitis B virus (HBV) has been associated with chronic active liver disease with acute exacerbations and a high relapse rate after an initial response to alpha-interferon (IFN-alpha) therapy. Poor sustained response has been correlate...

Topics

Adult
Amino Acid Sequence
Antiviral Agents
Codon
Female
Genetic Variation
Hepatitis B Core Antigens
Hepatitis B e Antigens
Hepatitis B, Chronic
Humans
Interferon-alpha
Male
Middle Aged
Molecular Sequence Data
Multivariate Analysis
Mutation
Prognosis
Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 9764979
DOI: 10.1016/s0168-8278(98)80050-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9764979-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics