Gradual accumulation of mutations in precore core region of HBV in patients with chronic active hepatitis: implications of clustering changes in a small region of the HBV core region.

doi:10.1002/(SICI)1096-9071(199601)48:1<38::AID-JMV6>3.0.CO;2-M

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Article

Gradual accumulation of mutations in precore core region of HBV in patients with chronic active hepatitis: implications of clustering changes in a small region of the HBV core region.

Journal of medical virology - 1 Jan 1996

Hur G M, Lee Y I, Suh D J, Lee J H, Lee Y I

Abstract excerpt

The sequence in the precore and core region of the hepatitis B virus (HBV) genome in the serum of five chronic active hepatitis patients at four different stages in each individual were studied by polymerase chain reaction and DNA sequencing to determine the prevalence and type of precore and cor...

Topics

Adolescent
Adult
Amino Acid Sequence
Base Sequence
Codon, Terminator
DNA, Viral
Disease Progression
Female
Genes, Viral
Hepatitis B
Hepatitis B Core Antigens
Hepatitis B virus
Hepatitis, Chronic
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation

Source

Open in PubMed

Identifiers

PMID: 8825708
DOI: 10.1002/(SICI)1096-9071(199601)48:1<38::AID-JMV6>3.0.CO;2-M

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8825708-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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