Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing.

World journal of gastroenterology - 14 Nov 2012

Homs Maria, Buti Maria, Tabernero David, Quer Josep, Sanchez Alex, Corral Noelia, Esteban Rafael, Rodriguez-Frias Francisco

Abstract excerpt

AIM: To investigate the variability of the main immunodominant motifs of hepatitis B virus (HBV) core gene by ultra-deep-pyrosequencing (UDPS). METHODS: Four samples (2 genotype A and 2 genotype D) from 4 treatment-naïve patients were assessed for baseline variability. Two additional samples from one patient (patient 4, genotype D) were selected for analysis: one sample corresponded to a 36-mo treatment-free...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Hepatitis B, Chronic

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Immunodominant Epitopes

Share to Mutagenesis, Site-Directed

Source

Open in PubMed Open full text

Identifiers

PMID: 23155338
DOI: 10.3748/wjg.v18.i42.6096
PMCID: PMC3496886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing.PMID 23155338Read ↗

Whole genome characterization of hepatitis B virus quasispecies with massively parallel pyrosequencing.Semantic proximity Read ↗

Quasispecies structure, cornerstone of hepatitis B virus infection: mass sequencing approach.Semantic proximity Read ↗

Characterization of Full-Length Genomes of Hepatitis B Virus Quasispecies in Sera of Patients at Different Phases of Infection.Semantic proximity Read ↗

Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome.Semantic proximity Read ↗

Comparison of next-generation sequencing and clone-based sequencing in analysis of hepatitis B virus reverse transcriptase quasispecies heterogeneity.Semantic proximity Read ↗

Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.Semantic proximity Read ↗

Multiple Hepatitis B Virus (HBV) Quasispecies and Immune-Escape Mutations Are Present in HBV Surface Antigen and Reverse Transcriptase of Patients With Acute Hepatitis B.Semantic proximity Read ↗

Ultra-deep sequencing reveals high prevalence and broad structural diversity of hepatitis B surface antigen mutations in a global population.Semantic proximity Read ↗

Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution.Semantic proximity Read ↗

Adaptive Evolution and Distinct Mutation Signatures of Full-Length HBV Quasispecies in HBeAg-Negative Chronic Hepatitis B.Semantic proximity Read ↗

Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression.Semantic proximity Read ↗

Virus evolution during chronic hepatitis B virus infection as revealed by ultradeep sequencing data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.