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2′-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family

9 Feb 2011

Abstract excerpt

The 5' cap of human messenger RNA consists of an inverted 7-methylguanosine linked to the first transcribed nucleotide by a unique 5'-5' triphosphate bond followed by 2'-O-ribose methylation of the first and often the second transcribed nucleotides, likely serving to modify efficiency of transcript processing, translation and stability. We report the validation of a human enzyme that methylates the ribose of the...

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PMID: 21310715
DOI: 10.1093/nar/gkr038

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2′-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile familyPMID 21310715Read ↗

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