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Article

Complementation of Rickettsia rickettsii RelA/SpoT restores a nonlytic plaque phenotype.

Infection and immunity - 1 Apr 2011

Clark Tina R, Ellison Damon W, Kleba Betsy, Hackstadt Ted

Abstract excerpt

Spotted fever group rickettsiae are known to produce distinct plaque phenotypes. Strains that cause lytic infections in cell culture form clear plaques, while nonlytic strains form opaque plaques in which the cells remain intact. Clear plaques have historically been associated with more-virulent species or strains of spotted fever group rickettsiae. We have selected spontaneous mutant pairs from two independent...

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Identifiers

PMID: 21300770
DOI: 10.1128/IAI.00048-11
PMCID: PMC3067566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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