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Article

Comparative genome sequencing of Rickettsia rickettsii strains that differ in virulence.

Infection and immunity - 1 Apr 2015

Clark Tina R, Noriea Nicholas F, Bublitz DeAnna C, Ellison Damon W, Martens Craig, Lutter Erika I, Hackstadt Ted

Abstract excerpt

Rickettsia rickettsii is an obligate intracellular pathogen that is the causative agent of Rocky Mountain spotted fever. Strains of R. rickettsii differ dramatically in virulence. In a guinea pig model of infection, the severity of disease as assessed by fever response varies from the most virulent, Sheila Smith, to Iowa, which causes no fever. To identify potential determinants of virulence in R. rickettsii, the...

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Share to Bacterial Outer Membrane Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25644009
DOI: 10.1128/IAI.03140-14
PMCID: PMC4363411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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